Farko da ƙarshen bincike kan Jinming Film, kyakkyawan dabara don kare murya

A shekarar 1983, Ma'aikatar Lafiya ta Lardin Shandong ta ba da umarni ga masana'antar magungunan gargajiya ta kasar Sin ta Jinan (wanda yanzu haka ake kira Jinan Traditional Medicines Factory) Hongjitang Magunguna) don haɓaka magani don magancewa da kare makogwaro. Allunan Jinming sun fara bincike da haɓaka a cikin 1987, kuma sun sadaukar da kansu ga hakan. A ƙarshe, an haɓaka su cikin nasara a watan Yunin 1990 kuma sun sami takardar shaidar sabbin magunguna ta ƙasa da lambar amincewa a cikin 1991. An saka su a kasuwa a cikin 1992. Daga baya, a watan Mayun 1994, alluna na Jinming sun lashe kyautar farko ta lambar yabo ta Jinan Science and Technology Development Award.

Allunan Jinming suna cikin shahararrun magunguna, waɗanda aka haɓaka su da kyau bisa ga ka'idar ƙarfafa jiki da ƙarfafa tushen maganin gargajiya na ƙasar Sin. Suna da dabarun gargajiya daga daular Ming da Qing da kuma shahararrun magunguna na zamani. A cikin "Takardar Shaidar Gano Nasarorin Kimiyya da Fasaha" na Jinming Film, akwai wani littafi da ke cewa: "Dangane da magungunan gargajiya na kasar Sin, an yi amfani da" Tie Di Wan "daga Gong Tingxian" Shoushi Baoyuan "a Daular Ming," Bing Bo San "daga Chen Shigong" Tabbacin Tiyata ", da" Zeng Ye Tang "daga Wu Jutong" Wen Bing Tiao Bian "a Daular Qing a matsayin tushen rubuta magunguna masu mahimmanci. Jinming Film ya kuma karɓi maganin kiyaye makogwaro na tsohon likitan kiwon lafiya na Peking Opera na kasar Sin Zheng Zhi, tare da shekaru na gwaje-gwajen asibiti da gyare-gyare ga nau'in magani, kuma a ƙarshe ya ƙirƙiri Jinming Film. Kafin samar da shi, ya yi bincike mai tsauri da tsari kan magunguna, magunguna, guba, gwaji na dabbobi, da kuma binciken asibiti. Jumlar ita ce:. An rubuta waɗannan rukunonin bincike a cikin adabi. A ranar 30 ga Janairu, 1989, an kammala binciken pharmacodynamics a Kwalejin Kiwon Lafiya ta Mount Taishan. An ɗauko ƙarshen daga Gwajin maganin kumburi na allunan Jinming shine, bisa ga binciken asibiti na farko, allunan Jinming suna da kyakkyawan tasirin magani akan alamu kamar su pharyngitis mai tsanani da na yau da kullun, kumburin murya, ciwon makogwaro, da kuma ƙarar murya. A lokaci guda, a cikin gwaje-gwajen ƙwayoyin cuta, an kuma tabbatar da cewa allunan Jinming suna da wasu tasirin ƙwayoyin cuta. A ranar 10 ga Fabrairu na wannan shekarar, allunan Jinming sun kammala nazarin guba a Sashen Koyarwa da Bincike na Magunguna na Kwalejin Likitancin Mount Taishan. Duk ma'aikata masu bincike ne daga Sashen Koyarwa da Bincike na Magunguna na Makarantar Likitancin Jami'ar Shandong. Ta hanyar kafa gwaje-gwaje daban-daban da suka shafi cututtukan makogwaro, an yanke hukunci mai zuwa: matsakaicin haƙurin baki na beraye ya wuce 5.12 g/kg (sau 436 na maganin yau da kullun ga mutane), yana nuna cewa maganin yana da aminci; Ba a sami alamun guba mai tsanani ba na tsawon kwanaki 7 a jere; Tsawon kwanaki 30 a jere, ba a sami alamun guba mai tarin yawa ba. An gudanar da gwaje-gwajen guba na dogon lokaci na tsawon kwanaki 75 a jere, kuma babu wani bambanci mai mahimmanci a cikin adadin ƙwayoyin jinin ja da fari, alanine aminotransferase, da gano nitrogen na urea kafin da bayan amfani.

A shekarar 1991, masu bincike daga Dakin Gwaji na Magunguna sun gudanar da gwaje-gwajen gwaji kan ƙwayoyin halittar Jinming. An lura da tasirin ƙwayoyin halittar Jinming kan kumburin ƙwayoyin halittar murya a cikin zomaye da man croton ya haifar ta hanyar shafa ƙwayoyin halittar murya a cikin gida. Sakamakon ya nuna cewa maganin man waken soya kashi 2% yana da tasirin kumburi mai yawa akan ƙwayar halittar zomaye, kuma tasirinsa ya tabbata. Kwayoyin halittar Jinming na iya magance tasirin kumburin man croton sosai, wanda ke nuna amincin alamun.

Bayan gwaje-gwajen dabbobi, shiga binciken asibiti. Ƙungiyar binciken ta ɗauki mutane daga sana'o'i daban-daban kuma ta rubuta yadda suke amfani da ƙwayoyin Jinming. Ta hanyar kimantawa mai zurfi da nazarin bayanai, ingancin ƙwayoyin Jinming akan alamun kamar ciwo, bushewa, ƙonewa, ƙaiƙayi, majina, jin jikin waje, kumburi, da ƙara a cikin pharyngitis mai tsanani da na yau da kullun da sauran cututtuka ya wuce 80%. Ingancin ƙwayoyin Jinming akan alamun kamar zafi, bushewa, ƙonewa, ƙaiƙayi, da jin jikin waje ya yi fice musamman, amma babu wani bambanci mai mahimmanci idan aka kwatanta da ƙungiyar kulawa mai kyau. Akwai babban bambanci a cikin raguwar ƙwayoyin jinin fari tsakanin ƙungiyar gwaji da ƙungiyar kulawa mai kyau, wanda ke nuna cewa ƙwayoyin Jinming suna da wani tasirin hana kumburi.

Fiye da shekaru 30, a matsayin samfurin Hongjitang Pharmaceutical da kuma nau'ikan magungunan gargajiya na kasar Sin da aka kare, Jinming Tablet ba wai kawai ta sami karbuwa sosai ba, har ma ta lashe kyautar ci gaban kimiyya da fasaha ta shekara-shekara ta Ma'aikatar Al'adu, kyautar gudummawa ta musamman ta ci gaban kimiyya da fasaha ta masana'antar magunguna ta Shandong, kyautar farko ta Jinan Science and Technology Development Award, da kuma kyautar magunguna na gargajiya na kasar Sin da shirye-shirye masu sauki. An amince da ita a matsayin wata alama mai suna a Jinan, ta zama babbar alama ta Hongjitang Pharmaceutical.