Ukuqala nokuphela kophando kwiJinming Film, indlela efanelekileyo yokukhusela ilizwi
Ngo-1983, iSebe lezeMpilo lePhondo laseShandong layalela iJinan Traditional Chinese Medicine Factory (ngoku eHongjitang Pharmaceutical) ukuze kuphuhliswe iyeza lokunyanga nokukhusela umphimbo. Iipilisi zeJinming zaqala uphando nophuhliso ngo-1987, zaza zazinikele kulo. Ekugqibeleni, zaphuhliswa ngempumelelo ngoJuni 1990 zaza zafumana isatifikethi esitsha seyeza likazwelonke kunye nenombolo yokuvunywa ngo-1991. Zafakwa kwimarike ngo-1992. Emva koko, ngoMeyi 1994, iipilisi zeJinming zaphumelela ibhaso lokuqala leJinan Science and Technology Progress Award.
Iipilisi zeJinming zezemithi edumileyo, eziphuhliswe ngononophelo ngokusekelwe kwingcamango yokuqinisa umzimba nokuqinisa isiseko samayeza emveli aseTshayina. Zineendlela zakudala ezivela kubukhosi bukaMing noQing kunye nemithi edumileyo yanamhlanje. Kwi "Satifikethi sokuQondwa kweeMpumelelo zeSayensi neTekhnoloji" zeJinming Film, kukho ingxelo ethi: "Ngokusekelwe kwimiyalelo yemveli yamayeza aseTshayina, i" Tie Di Wan "evela kuGong Tingxian" Shoushi Baoyuan "kwiMing Dynasty," uBing Bo San "evela kuChen Shigong's" Surgical Authenticity ", kunye no" Zeng Ye Tang "evela kuWu Jutong" Wen Bing Tiao Bian "kwiQing Dynasty zasetyenziswa njengesiseko sokunikezelwa kwamayeza abalulekileyo. I-Jinming Film yamkela neyeza lokugcina umphimbo logqirha wangaphambili wezempilo waseTshayina uZheng Zhi, idibene neminyaka yovavanyo lweklinikhi kunye nokuguqulwa kwifom yedosi, kwaye ekugqibeleni yaphuhlisa iJinming Film. Ngaphambi kokuba iveliswe, yadlula kuphando olungqongqo nolucwangcisiweyo lwezamayeza, lwezamayeza, lwetyhefu, lwezilwanyana, kunye nolweklinikhi. Isivakalisi sithi:. Amaqela alandelayo ezifundo abhalwe kwiincwadi. Ngomhla wama-30 kuJanuwari 1989, uphando lwezamayeza lwagqitywa kwiKholeji yezoNyango yaseMount Taishan. Isigqibo esithathwe kuvavanyo lokulwa nokuvuvukala lwe Iipilisi zeJinming zithi, ngokweengxelo zokuqala zeklinikhi, iipilisi zeJinming zinemiphumo emihle yonyango kwiimpawu ezifana ne-acute and chronic pharyngitis, ukudumba kwe-vocal cord, umphimbo obuhlungu, kunye nokurhawuzelela. Kwangaxeshanye, kwiimvavanyo ze-antibacterial, kwaqinisekiswa ukuba iipilisi zeJinming zinemiphumo ethile ye-antibacterial. Ngomhla we-10 kuFebruwari waloo nyaka, iipilisi zeJinming zagqiba uphando lwe-toxicology kwiCandelo le-Pharmacology Teaching and Research leMount Taishan Medical College. Bonke abasebenzi ngabaphandi abavela kwiCandelo le-Pharmacology Teaching and Research leShandong University School of Medicine. Ngokuseka iimvavanyo ezahlukeneyo zeempuku ezinxulumene nezifo zomqala, kwafikelelwa kwizigqibo ezilandelayo: ukunyamezela okuphezulu komlomo kweempuku kudlule i-5.12 g/kg (ixesha eliphindwe ngama-436 ledosi yemihla ngemihla ebantwini), okubonisa ukuba iyeza likhuselekile; Akukho zimpawu zetyhefu ezibukhali ezifunyenweyo iintsuku ezisi-7 ezilandelelanayo; Kwiintsuku ezingama-30 ezilandelelanayo, akukho zimpawu zetyhefu ezifunyenweyo. Iimvavanyo zetyhefu zexesha elide zenziwe iintsuku ezingama-75 ezilandelelanayo, kwaye akukho mahluko abalulekileyo kwiinombolo zeeseli zegazi ezibomvu nezimhlophe, i-alanine aminotransferase, kunye nokufunyanwa kwe-urea nitrogen ngaphambi nasemva kokusetyenziswa.
Ngo-1991, abaphandi abavela kwiLabhoratri yePharmacology benze uvavanyo lokuvuvukala kwezilwanyana kwiipilisi zeJinming. Isiphumo seepilisi zeJinming ekuvuvukeni kovavanyo lweentambo zelizwi kwimivundla ebangelwa yioyile yecroton sabonwa ngokuhlikihla iintambo zelizwi kwindawo ethile. Iziphumo zabonisa ukuba isisombululo seoyile yesoya ye-2% sasinefuthe elikhulu lokuvuvukala kwizicubu zentambo yelizwi kwimivundla, kwaye isiphumo saso sasizinzile. Iipilisi zeJinming zinokulwa kakhulu neziphumo zokuvuvukala zeoyile yecroton, nto leyo ebonisa ukuthembeka kwezalathisi.
Emva kovavanyo lwezilwanyana, ngena kuphando lweklinikhi. Iqela lophando liqeshe abantu abavela kwimisebenzi eyahlukeneyo kwaye barekhoda ukusebenzisa kwabo iithebhulethi zeJinming. Ngokusebenzisa uqikelelo olucokisekileyo kunye nohlalutyo lwedatha, izinga elisebenzayo leethebhulethi zeJinming kwiimpawu ezifana nentlungu, ukoma, ukutsha, ukurhawuzelela, isikhwehlela, imvakalelo yomzimba wangaphandle, ukudumba, kunye nokurhawuzelela kwi-pharyngitis ebukhali nengapheliyo kunye nezinye izifo lalingaphezulu kwama-80%. Ukusebenza kakuhle kweethebhulethi zeJinming kwiimpawu ezifana nentlungu, ukoma, ukutsha, ukurhawuzelela, kunye nemvakalelo yomzimba wangaphandle kwakumangalisa kakhulu, kodwa kwakungekho mahluko ubalulekileyo xa kuthelekiswa neqela lolawulo oluhle. Kukho umahluko obalulekileyo ekunciphiseni kweeseli zegazi ezimhlophe phakathi kweqela lovavanyo kunye neqela lolawulo oluhle, okubonisa ukuba iithebhulethi zeJinming zinefuthe elithile lokulwa nokuvuvukala.
Kangangeminyaka engaphezu kwama-30, njengemveliso ekhethekileyo yeHongjitang Pharmaceutical kunye nohlobo olukhuselweyo lwesizwe lwamayeza emveli aseTshayina, iJinming Tablet ayimkelwanga nje kuphela ngokubanzi, kodwa ikwaphumelele ibhaso lonyaka lenkqubela phambili yesayensi netekhnoloji leSebe leNkcubeko, ibhaso "lesibhozo leminyaka emihlanu" lenkxaso ekhethekileyo yenzululwazi netekhnoloji kwishishini lamayeza laseShandong, ibhaso lokuqala leMbasa yeNqubekela phambili yeSayensi neTekhnoloji yaseJinan, kunye nebhaso lamayeza emveli aseTshayina abalaseleyo kunye nokulungiswa okulula. Iqatshelwe njengophawu oludumileyo eJinan, yaba yikhadi eliqaqambileyo leHongjitang Pharmaceutical.