Ukuqala nokuphela kocwaningo nge-Jinming Film, ifomula enhle yokuvikela izwi
Ngo-1983, uMnyango Wezempilo weSifundazwe saseShandong wayala iJinan Traditional Chinese Medicine Factory (manje eyi-1983). I-Hongjitang I-Pharmaceutical) ukuthuthukisa umuthi wokwelapha nokuvikela umphimbo. Amaphilisi e-Jinming aqala ucwaningo nokuthuthukiswa ngo-1987, futhi azinikela kuwo. Ekugcineni, athuthukiswa ngempumelelo ngoJuni 1990 futhi athola isitifiketi semithi esisha sikazwelonke kanye nenombolo yokuvunyelwa ngo-1991. Afakwa emakethe ngo-1992. Ngemva kwalokho, ngoMeyi 1994, amaphilisi e-Jinming awina umklomelo wokuqala we-Jinan Science and Technology Progress Award.
Amaphilisi e-Jinming ayingxenye yemithi edumile, athuthukiswe ngokucophelela ngokusekelwe embonweni wokuqinisa umzimba nokuqinisa isisekelo semithi yendabuko yaseShayina. Anezindlela zakudala ezivela ebukhosini bukaMing noQing kanye nemithi edumile yesimanje. Ku-"Certificate of Identification of Scientific and Technological Achievements" ye-Jinming Film, kukhona irekhodi elithi: "Ngokusekelwe emithini yendabuko yaseShayina, i-" Tie Di Wan "evela ku-" Shoushi Baoyuan kaGong Tingxian" e-Ming Dynasty," i-Bing Bo San "evela ku-" Surgical Authenticity" kaChen Shigong, kanye ne-" Zeng Ye Tang "evela ku-" Wen Bing Tiao Bian kaWu Jutong "e-Qing Dynasty" yasetshenziswa njengesisekelo sokunikezwa imithi ebalulekile. I-Jinming Film yamukele futhi imithi yokulondoloza umphimbo yodokotela wezempilo wangaphambili we-Chinese Peking Opera uZheng Zhi, kuhlanganiswe neminyaka yokuhlolwa kwezokwelapha kanye nokuguqulwa kwefomu lomthamo, futhi ekugcineni yathuthukisa i-Jinming Film. Ngaphambi kokukhiqizwa kwayo, yadlula ocwaningweni oluqinile noluhlelekile lwezokwelapha, lwezokwelapha, lwezokwelapha, lwezilwane, kanye nolwezokwelapha. Umusho uthi:. Amaqembu alandelayo ezifundo alotshwe ezincwadini. Ngomhlaka-30 Januwari 1989, ucwaningo lwe-pharmacodynamics lwaqedwa eMount Taishan Medical College. Isiphetho esithathwe ekuhlolweni kokulwa nokuvuvukala kwe- Amaphilisi e-Jinming awukuthi, ngokusho kokubonwa kokuqala kwezokwelapha, amaphilisi e-Jinming anemiphumela emihle yokwelapha ezimpawini ezifana ne-pharyngitis ebukhali nehlala isikhathi eside, ukuvuvukala kwe-vocal cord, umphimbo obuhlungu, kanye nokuhosha. Ngesikhathi esifanayo, ekuhlolweni kwamagciwane, kwaqinisekiswa nokuthi amaphilisi e-Jinming anemiphumela ethile yokulwa namagciwane. NgoFebhuwari 10 walowo nyaka, amaphilisi e-Jinming aqedela ucwaningo lwe-toxicology eSigabeni Sokufundisa Nokucwaninga Nge-Pharmacology se-Mount Taishan Medical College. Bonke abasebenzi bangabacwaningi abavela eMnyangweni Wokufundisa Nokucwaninga Nge-Pharmacology we-Shandong University School of Medicine. Ngokusungula izivivinyo ezahlukahlukene zamagundane ezihlobene nezifo zomphimbo, kwatholakala iziphetho ezilandelayo: ukubekezelela okuphezulu kwamagundane ngomlomo kudlule u-5.12 g/kg (izikhathi ezingu-436 zomthamo wansuku zonke kubantu), okubonisa ukuthi umuthi uphephile; Azikho izimpawu zobuthi obubukhali ezitholakale izinsuku ezingu-7 zilandelana; Ezinsukwini ezingu-30 zilandelana, azikho izimpawu zobuthi obuqongelelekayo ezitholakale. Izivivinyo zobuthi zesikhathi eside zenziwa izinsuku ezingu-75 zilandelana, futhi bekungekho mehluko omkhulu ekubalweni kwamangqamuzana egazi abomvu namhlophe, i-alanine aminotransferase, kanye nokutholwa kwe-urea nitrogen ngaphambi nangemva kokuphathwa.
Ngo-1991, abacwaningi base-Pharmacology Laboratory benze izivivinyo zokuvuvukala kwezilwane kumaphilisi e-Jinming. Umphumela wamaphilisi e-Jinming ekuvuvukeni kokuhlolwa kwezintambo zezwi konogwaja okubangelwa uwoyela we-croton wabonwa ngokuhlikihla izintambo zezwi endaweni. Imiphumela yabonisa ukuthi isisombululo samafutha e-soya angu-2% sasinomphumela omkhulu wokuvuvukala ezicutshini zezintambo zezwi zonogwaja, futhi umphumela waso wawuzinzile. Amaphilisi e-Jinming angamelana kakhulu nemiphumela yokuvuvukala kwamafutha e-croton, okubonisa ukuthembeka kwezinkomba.
Ngemva kokuhlolwa kwezilwane, ngena ocwaningweni lwezokwelapha. Ithimba locwaningo liqoqe abantu abavela emisebenzini ehlukene futhi laqopha ukusetshenziswa kwabo kwamaphilisi e-Jinming. Ngokusebenzisa ukulinganisa okuqinile kanye nokuhlaziywa kwedatha, izinga eliphumelelayo lamaphilisi e-Jinming ezimpawu ezifana nobuhlungu, ukoma, ukusha, ukulunywa, isikhwehlela, umuzwa womzimba wangaphandle, ukuvuvukala, kanye nokuhosha kwe-pharyngitis ebukhali nehlala njalo kanye nezinye izifo lalingaphezu kuka-80%. Ukusebenza kahle kwamaphilisi e-Jinming ezimpawu ezifana nobuhlungu, ukoma, ukusha, ukulunywa, kanye nomuzwa womzimba wangaphandle kwakuvelele kakhulu, kodwa kwakungekho mehluko obalulekile uma kuqhathaniswa neqembu lokulawula elihle. Kunomehluko obalulekile ekwehleni kwamaseli amhlophe egazi phakathi kweqembu lokuhlola kanye neqembu lokulawula elihle, okubonisa ukuthi amaphilisi e-Jinming anomphumela othile wokulwa nokuvuvukala.
Sekuyiminyaka engaphezu kwengu-30, njengomkhiqizo okhethekile we-Hongjitang Pharmaceutical kanye nohlobo oluvikelwe lukazwelonke lwemithi yendabuko yaseShayina, i-Jinming Tablet ayigcinanga nje ngokwamukelwa kabanzi, kodwa futhi iwine umklomelo waminyaka yonke wentuthuko yesayensi nezobuchwepheshe woMnyango Wezamasiko, umklomelo "wesishiyagalombili weminyaka emihlanu" wentuthuko yesayensi nezobuchwepheshe ekhethekile embonini yemithi yaseShandong, umklomelo wokuqala we-Jinan Science and Technology Progress Award, kanye nomklomelo omuhle kakhulu wemithi yendabuko yamaShayina enelungelo lobunikazi kanye nomklomelo wokulungiselela olula. Iqashelwe njengomkhiqizo odumile eJinan, yaba ikhadi elikhazimulayo le-Hongjitang Pharmaceutical.