Chiyambi ndi mapeto a kafukufuku pa Jinming Film, njira yabwino yotetezera mawu

Mu 1983, Dipatimenti ya Zaumoyo ya Chigawo cha Shandong inalamula fakitale ya mankhwala achi China ya Jinan Traditional Chinese Medicine Factory (yomwe tsopano ndi Hongjitang Mankhwala (Pharmaceutical) kuti apange mankhwala ochizira ndi kuteteza pakhosi. Mapiritsi a Jinming adayamba kafukufuku ndi chitukuko mu 1987, ndipo adadzipereka pa izi. Pomaliza, adapangidwa bwino mu June 1990 ndipo adapeza satifiketi yatsopano yadziko lonse komanso nambala yovomerezeka mu 1991. Adayikidwa pamsika mu 1992. Pambuyo pake, mu Meyi 1994, mapiritsi a Jinming adapambana mphoto yoyamba ya Jinan Science and Technology Progress Award.

Mapiritsi a Jinming ndi a mankhwala otchuka, opangidwa mosamala kutengera chiphunzitso cholimbitsa thupi ndi kulimbitsa maziko a mankhwala achikhalidwe aku China. Ali ndi njira zakale zochokera ku mafumu a Ming ndi Qing komanso mankhwala otchuka amakono. Mu "Satifiketi Yodziwitsa Zomwe Zachitika Pasayansi ndi Ukadaulo" ya Jinming Film, pali mbiri yakuti: "Kutengera mankhwala achikhalidwe aku China," Tie Di Wan "wochokera kwa Gong Tingxian" Shoushi Baoyuan "mu Ming Dynasty," Bing Bo San "wochokera kwa Chen Shigong's" Surgical Authenticity ", ndi" Zeng Ye Tang "wochokera kwa Wu Jutong's" Wen Bing Tiao Bian "mu Qing Dynasty adagwiritsidwa ntchito ngati maziko a mankhwala ofunikira. Jinming Film idavomerezanso mankhwala osungira pakhosi a master wa Peking Opera waku China Mei Lanfang, dokotala wakale wazachipatala, Zheng Zhi, kuphatikiza zaka zambiri za mayeso azachipatala ndikusintha kwa mlingo, ndipo pomaliza pake idapanga Jinming Film. Isanapangidwe, idachita kafukufuku wokhwima komanso wokhazikika wamankhwala, wamankhwala, wa poizoni, wa nyama, komanso wazachipatala. Chiganizo ndi ichi:. Magulu otsatirawa a maphunziro alembedwa m'mabuku. Pa Januwale 30, 1989, kafukufuku wa mankhwala adamalizidwa ku Mount Taishan Medical College. Chomaliza chomwe chidachokera ku kuyesa koletsa kutupa kwa Mapiritsi a Jinming ndi akuti, malinga ndi zomwe zapezeka kuchipatala, mapiritsi a Jinming ali ndi zotsatira zabwino zochizira zizindikiro monga pharyngitis yoopsa komanso yosatha, kutupa kwa mawu, pakhosi, komanso kuwomba. Nthawi yomweyo, mu zoyeserera zotsutsana ndi mabakiteriya, zidatsimikiziridwanso kuti mapiritsi a Jinming ali ndi zotsatira zina zotsutsana ndi mabakiteriya. Pa February 10 chaka chomwecho, Mapiritsi a Jinming adamaliza kafukufuku wa poizoni mu Gawo Lophunzitsa ndi Kafukufuku wa Pharmacology ku Mount Taishan Medical College. Ogwira ntchito onse ndi ofufuza ochokera ku Dipatimenti Yophunzitsa ndi Kafukufuku wa Pharmacology ku Shandong University School of Medicine. Mwa kukhazikitsa zoyeserera zosiyanasiyana zokhudzana ndi matenda a pakhosi, mfundo zotsatirazi zidapezeka: kulekerera kwakukulu kwa mbewa pakamwa kudapitilira 5.12 g/kg (nthawi 436 kuposa mlingo watsiku ndi tsiku kwa anthu), zomwe zikusonyeza kuti mankhwalawa ndi otetezeka; Palibe zizindikiro za poizoni woopsa zomwe zidapezeka kwa masiku 7 otsatizana; Kwa masiku 30 otsatizana, palibe zizindikiro za poizoni wochuluka zomwe zidapezeka. Zoyeserera za poizoni wa nthawi yayitali zidachitika kwa masiku 75 otsatizana, ndipo panalibe kusiyana kwakukulu pakuwerengera maselo ofiira ndi oyera m'magazi, alanine aminotransferase, ndi kuzindikira nayitrogeni wa urea asanayambe komanso atalandira.

Mu 1991, ofufuza ochokera ku Pharmacology Laboratory adachita zoyeserera zotupa za nyama pa mapiritsi a Jinming. Zotsatira za mapiritsi a Jinming pa zoyeserera zotupa za mitsempha ya mawu mwa akalulu omwe amayambitsidwa ndi mafuta a croton zidawonedwa popaka mitsempha ya mawu m'deralo. Zotsatira zake zidawonetsa kuti yankho la mafuta a soya la 2% linali ndi mphamvu yayikulu yotupa pa minofu ya mitsempha ya mawu ya akalulu, ndipo mphamvu yake inali yokhazikika. Mapiritsi a Jinming amatha kuthana kwambiri ndi zotsatira zotupa za mafuta a croton, zomwe zikusonyeza kudalirika kwa zizindikiro.

Pambuyo poyesa nyama, lowani kafukufuku wazachipatala. Gulu lofufuza linalemba anthu ochokera m'magawo osiyanasiyana ndikulemba momwe amagwiritsira ntchito mapiritsi a Jinming. Kudzera mu kuwerengera kozama komanso kusanthula deta, kuchuluka kogwira mtima kwa mapiritsi a Jinming pa zizindikiro monga kupweteka, kuuma, kutentha, kuyabwa, sputum, kumva thupi lachilendo, kutupa, ndi mawu omveka bwino mu pharyngitis yoopsa komanso yosatha ndi matenda ena kunali kopitilira 80%. Kugwira ntchito kwa mapiritsi a Jinming pa zizindikiro monga kupweteka, kuuma, kutentha, kuyabwa, ndi kumva thupi lachilendo kunali kodabwitsa kwambiri, koma panalibe kusiyana kwakukulu poyerekeza ndi gulu lowongolera labwino. Pali kusiyana kwakukulu pakuchepa kwa maselo oyera amagazi pakati pa gulu loyesera ndi gulu lowongolera labwino, zomwe zikusonyeza kuti mapiritsi a Jinming ali ndi mphamvu yotsutsa kutupa.

Kwa zaka zoposa 30, monga mankhwala apadera a Hongjitang Pharmaceutical ndi mitundu yosiyanasiyana ya mankhwala achikhalidwe aku China otetezedwa mdziko lonse, Jinming Tablet sikuti yangolandiridwa kwambiri, komanso yapambana mphoto yapachaka ya kupita patsogolo kwa sayansi ndi ukadaulo ya Unduna wa Zachikhalidwe, mphotho ya "zaka zisanu ndi zitatu" ya kupita patsogolo kwa sayansi ndi ukadaulo yapadera yamakampani opanga mankhwala ku Shandong, mphotho yoyamba ya Mphoto ya Kupita Patsogolo kwa Sayansi ndi Ukadaulo wa Jinan, ndi mphotho yabwino kwambiri ya mankhwala achikhalidwe aku China komanso mankhwala osavuta okonzekera. Yadziwika ngati mtundu wotchuka ku Jinan, kukhala khadi lowala la Hongjitang Pharmaceutical.