Ergothioneine

Ergothionein is a powerful hypochlorous acid scavenger, and although many compounds can react with hypochlorous acid, few can react as quickly as ergothionein. A1- Anti protease inhibitors (APIs), such as elastase, are particularly sensitive to hypochlorous acid, and physiological concentrations of ergotamine can effectively protect APIs against inactivation caused by hypochlorous acid. As neutrophils are the main source of hypochlorous acid in the body, one of the functions of ergotamine is to protect red blood cells from harm from neutrophils in normal functioning or pathological inflammatory sites.
Ergothionein is a highly protective and non-toxic natural antioxidant that is not easily oxidized in water, allowing its concentration in certain tissues to reach mmol and stimulating the cell's natural antioxidant defense system. Ergothionein can chelate heavy metal ions, protecting red blood cells in the body from free radical damage.