I-Sodium Hyaluronate API zombini izicelo ze-Injection kunye ne-Eyedrop

Igama lemveliso: I-Sodium Hyaluronate/I-Hyaluronic Acid

I-CAS: 9067-32-7

Uvavanyo: 95.0%～105.0%

Ubunzulu bangaphakathiIxabiso elilinganisiweyo m³/kg

Ubunzima beMolekyuli: 800-3 yezigidi Da

Umsebenzi: I-Sodium Hyaluronate isetyenziswa kakhulu kwishishini le-nutraceuticals. Ingagaywa kwaye ifunxwe, yenza ulusu lube manzi, lugudileyo, luthambe kwaye luthambe; ibambezela ukuguga kwaye ithintele ukwenzeka kwe-arthritis kunye ne-brain atrophy I-Sodium hyaluronate yi-glycosaminoglycan eyinxalenye ebalulekileyo yesakhiwo se-cartilage yamalungu kwaye inoxanduva lwe-viscosity (ubukhulu) bolwelo lwe-synovial. Sinoluhlu olubanzi lwe-Sodium Hyaluronate oluvela kwi-800-300W mocelur weight onokukhetha ukuyisebenzisa kwiimveliso ezahlukeneyo.

Beka ubomi kwishelufa: iminyaka eyi-2

Qhagamshelana nathi

iinkcukacha zemveliso

I-Hyaluronic acid, ekwaziwa ngokuba yi-hyaluronan, i-HA kunye ne-uronic acid, yi-polysaccharide ethe tye eyenziwe ziiyunithi ze-disaccharide eziphindaphindayo ze-D-glucuronic acid kunye ne-N-acetyl-glucosamine.

Ayixutywanga okanye ibotshelelwe kwi-covalently kwiiproteni, kodwa ikhona ngohlobo lwee-complexes ezikhululekileyo okanye ezingezizo ze-covalent. Ulwakhiwo lwayo lulula kodwa ubunzima beemolekyuli bukhulu kakhulu.

Inkcazo yeBanga le-MTOE.

Inkcazo yeBanga le-MTOE

Izinto zovavanyo	Umgangatho	Izinto zovavanyo	Umgangatho
Inkangeleko	Umgubo okanye igranule emhlophe okanye ephantse ibe mhlophe	Isinyithi/（mg/kg）	≤ 80
Ukuchongwa	A. I-infrared absorption spectrophotomet	Ubalo lweebhaktheriya/（CFU/g）	≤100
	B. Inika impendulo (a) yesodium	Iimbumba kunye negwele (CFU/g)	≤50
Ilahleko yokomisa	≤15.0%	I-Staphylococcus aureus/g	Okungalunganga
Ubunzulu bangaphakathi/	Ixabiso elilinganisiweyo	I-Pseudomonas aeruginosa/g	Okungalunganga
（m³/kg）
Ubunzima beMolekyuli/（Da）	Ixabiso elilinganisiweyo	Ii-endotoxins zebhaktheriya/（IU/mg）
i-pH	5.0-8.5	I-Hemolysis	Okungalunganga
I-Nucleic Acid	A260nm≤ 0.5	I-Hemolytic streptococci	Okungalunganga
Inkangeleko yeSisombululo	I-A600nm≤ 0.01	Iintsalela ze-ethanol/（ppm）	≤4000
Iiproteni/%	≤0.1	I-sodium hyaluronate/（%）	95-105
Iikloridi/%	≤ 0.5	/	/

Isicelo

1. Utyando lwamehlo

Ikhusela iiseli ze-endothelial ze-cornea kumonakalo wezixhobo zotyando

Gcina ubunzulu kunye nemo yegumbi elingaphambili lamehlo ukuze kube lula ukwenza utyando

Ibonelela ngommandla ocacileyo wotyando kugqirha otyandayo

Ibonelela ngendawo ene-viscoelastic eyenza kube lula ukubekwa kwe-implant

2. I-Cartilage edibeneyo

Ukuthambisa, ukunciphisa ukungqubana

Nqanda ukuwohloka kwe-cartilage, khusela i-cartilage, kwaye ukhuthaze ukwakheka kwe-cartilage

Ukuvala imvakalelo ye-membrane, ukunciphisa iintlungu

Ilawula ukusebenza kweeseli kwaye ithintela i-angiogenesis

3. Unyango lwenxeba

I-HA ikhawulezisa izinga lokufuduka kweeseli ze-epithelial ezonakeleyo kwaye ikhuthaza ukuhlanganiswa kwee-macrophages ezifunekayo ekuphilisweni kwenxeba.

I-HA ikwathutha iiproteni ezithile kunye neepeptides ezifana nezinto ezikhulisayo ziye kwiindawo ezithintelweyo, nto leyo edlala indima ebalulekileyo ekuphilisweni kwenxeba.